People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...

Jen Culton learned she had the BRCA1 gene mutation after her older sister's breast-cancer diagnosis. She decided to have two of her daughters tested; one daughter also has the BRCA1 gene mutation.

(Medical Xpress) -- Working with human breast cells, researchers at the Johns Hopkins Kimmel Cancer Center have shown how the inactivation of a single copy of the breast cancer gene BRCA1 leaves ...

When it was discovered by researchers in 1994, the BRCA1 gene was hailed as a landmark achievement not just in breast cancer prevention but in medicine in general. Its discovery led to the ...

BRCA1 is one of the best-studied cancer genes in the world. Still, on occasion, doctors will test a patient and find a BRCA1 mutation no one has ever seen before. This creates a dilemma.

The BRCA1 gene is located on the long arm of chromosome 17, at position 17q21. The gene spans around 100 kilobases and codes for a protein containing 1863 amino acids. Mutations or alterations ...

(CNN) — Angelina Jolie’s stunning announcement that she had a preventive double mastectomy raised both awareness and questions about the gene that led to her decision — BRCA1. So what is the ...