The incidence of brain metastasis (BM) is high in patients with ... Novel agents, such as EGF receptor (EGFR) tyrosine kinase inhibitors (TKIs), have now been included in standard non-small ...

Anaplastic lymphoma kinase (ALK)-positive non-small cell ... with 12-month PFS rates of 78% for those with brain metastases, compared to only 22% for crizotinib[1][2]. This indicates that ...

Brain metastases stemming from lung cancer represent a common and ... In addition to the loss of EMT phenotype and overexpression of certain cytokines and receptor tyrosine kinase signaling pathways, ...

The heterogeneity of brain metastases highlights the differences from their primary ... The cognitive effects of new CNS-active therapies, such as tyrosine kinase inhibitors, immunotherapies, and ...

Objective: The purpose of this study was to explore the clinical characteristics, survival time and prognostic factors of patients undergoing craniotomy for brain metastases (BM ... patients receiving ...

In MYCN-amplified NB cells, the half-life of N-Myc is significantly prolonged due to binding and stabilization by Aurora kinase A (Aurora-A; elevated in NB), resulting in increased steady-state ...

A Personal View published in The Lancet Oncology challenges the long-standing perception of metastatic brain cancer, calling ...

DENVER (KDVR) — A man suspected of being a member of the Venezuelan gang Tren de Aragua was arrested in an apartment complex in Aurora on Saturday morning, federal agencies reported on X ...

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...

CENTENNIAL, Colo. (KDVR) — Three men accused of kidnapping and torturing a couple at an Aurora apartment complex were in court Monday. They had previously been in Immigration and Customs ...