Tirzepatide yielded greater cardiometabolic benefits, especially in total cholesterol, LDL cholesterol, and weight loss, ...

BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (MACEs). Mounting ...

Learn more about whether it's okay to take ibuprofen for pain relief while you're pregnant and if you're breastfeeding.

The low-risk group consistently demonstrated lower mean arterial pressure, UtA-PI, and sFlt-1 levels, along with higher PlGF ...

Drug repurposing is undervalued, but it offers potential benefits for patients and healthcare systems, argue Ruth Langley and colleagues Drug repurposing involves finding new indications for ...

Around 1 in 6 older adults take aspirin as their primary method of preventing cardiovascular disease—despite stricter guidelines that no longer always call for it, a study finds.

Practical Prescribing is a series produced in conjunction with the Drug and Therapeutics Bulletin to highlight important issues for prescribers to consider and prompts for shared decision making ...

Why Age 40-50 Males Need Closer Attention? Premature ASCVD is rising sharply in Indian men aged 40-50, demanding earlier ...

Aspirin inhibits the COX pathway and consequently diverts arachidonic acid metabolites to the LO pathway. This also leads to a decrease in the levels of PGE 2, the anti-inflammatory PG.

Aspirin prodrugs formed by derivatization at the benzoic acid group are very difficult to obtain because the promoiety accelerates the rate of hydrolysis by plasma esterases at the neighboring acetyl ...