Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

The ocular lens microcirculation system (MCS) is required to maintain transparency; however, how this system is established and maintained as a function of age is not well understood. Through its role ...

Recent studies uncovered an important role of aquaporins in cell migration, and migration-associated cell function such as angiogenesis, wound healing, and neutrophil motility. Here we provide ...

Recent studies have demonstrated that aquaporin (AQP) expression facilitates cell migration and promotes angiogenesis and neutrophil motility. Migration of tumor cells is a crucial step in tumor ...

The lymphatic system helps rid the body of toxins. Diseases of this system include lymphadenopathy, lymphoma and other disorders.

Work here is the first to test the hypothesis that Aquaporin-1 (AQP1) cation channels contribute to the monovalent component of Psickle. Human AQP1 channels expressed in Xenopus oocytes were evaluated ...

Localization in organelles and function analysis of aquaporin 1 (AQP1) protein in Ectropis obliqua (Lepidoptera: Geometridae) by Liang-De, Li; Ding-Feng, Wang; Feng-Jing, Liu; Hui, Zhang; Hui-Ling, Li ...

They are expecting that the mutation in aquaporin-1 will allow more water through, making blood vessels leaky. They will also investigate whether molecules in an important communication chain, called ...