The study of antipsychotic receptor binding is relatively new and still evolving. Although the specific receptor-binding profile of various atypical agents is increasingly well understood ...

Distinct pharmacologic profiles, especially actions on 5-hydroxytryptamine (5-HT) receptor subtypes, may contribute to the advantage of atypical antipsychotics in terms of adverse effects.

“This is a landmark finding that completely revises our understanding of the neural basis for psychosis and charts ... D2 receptors. Dopamine is a key for both receptors, but antipsychotics ...

In a statement, John Krystal, MD, editor of Biological Psychiatry, who was not involved in the research, said antipsychotics have "a wide range of receptor profiles. The stroke risk profiles from ...

To conduct the study, the researchers matched information from a large national database of insurance claims to what is known about the receptor binding profiles of the antipsychotic drugs.

‘Weight-loss drug that targets the serotonin 2c receptor may eliminate most of the metabolic changes caused by antipsychotic ... improved the metabolic profile of mice treated with olanzapine ...

Karuna Therapeutics focuses on developing therapies that target muscarinic cholinergic receptors ... clinical profile compared to first and second-generation antipsychotics that have been used ...

Now, scientists at the UNC School of Medicine and UC San Francisco (UCSF) have solved the first high-resolution crystal structure of the dopamine 2 receptor (DRD2) bound to the antipsychotic drug ...

They then eliminated most of these metabolic changes in mice co-treated with a weight-loss drug that targets the serotonin 2c receptor. "Atypical antipsychotics are essential medications for ...