Although several newer agents have recently gained approval, the mechanism of action of antipsychotics is still largely based on normalising dopaminergic neurotransmission which does not ...

A new Northwestern Medicine study has identified the molecular mechanisms that cause a commonly prescribed antipsychotic drug to produce harmful side effects similar to Parkinson's disease ...

In this follow-up, I’ll take a look at two new antipsychotic medications—ulotaront and xanomeline/trospium—that seem to have genuinely novel mechanisms of action and try to answer whether ...

are drugs that target certain neurotransmitters to manage the symptoms of mental health conditions. Antipsychotics are classified into two groups depending on their “mechanism of action,” or ...

Mechanisms of Q-Tc Interval Prolongation with Antidepressants and Antipsychotics Crumb and colleagues ... Though these drugs had little direct effect on cardiac ion channels, the effects that ...

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication ... pave the way for the development of ...

With only a few exceptions, these drugs were discovered by screening in animal models which do not discriminate on the basis of mechanism of action. Over the last 35 years, over 34,000 ...

The companies behind a prescription drug that ... are facing a class-action lawsuit over alleged “harmful side effects” to patients. The lawsuit relates to the antipsychotic drug Rexulti ...