"You can't fight what you can't see. We need better diagnostics to stop C. auris from spreading." Fungal pathogens are a major threat to public health as they are becoming more prevalent and resistant ...

This study aimed to repurpose the antifungal drug flucytosine (FCN) for anticancer activity together with cocrystals of nutraceutical coformers sinapic acid (SNP) and syringic acid (SYA). The ...

Leah Cowen reviews the mechanisms that potentiate the evolution of fungal drug resistance, with an emphasis on the central role of the molecular chaperone heat shock protein 90 (Hsp90) in altering ...

In an Editorial in July 2023, we wrote with optimism about the antifungal clinical development pipeline. At the time, several ...

Two bioactive ingredients in cannabis have been found to have antifungal properties when applied topically, according to a ...

However, scientists have now become increasingly aware that antifungal pesticides and antifungal drugs share some of the same mechanisms. The authors therefore warned that the promulgation of ...

The "In vitro" antifungal activity of ozonized sunflower oil (Bioperoxoil®) was tested on 101 samples of yeasts originating from onychomycosis using the disk diffusion method. The oil was efficacious ...

The Centers for Disease Control and Prevention notes that warmer conditions could also render existing antifungal measures less effective, and a study in The Lancet noted that over 2 million deaths ...

Plants employ abundant toxic secondary metabolites to withstand insect attack, while pollinators can tolerate some natural defensive compounds. Coumarins, as promising green alternatives to chemical ...