Prozac®, the trade name for the drug fluoxetine, was introduced to the U.S. market for the treatment of depression in 1988. Thirty years later, scientists still don't know exactly how the ...

Tricyclic antidepressants (TCAs) were among the first drugs developed to treat depression. They’ve been on the market since the 1950s. TCA mechanism of action ...

Lisa M. Monteggia, Ph.D., and Ege T. Kavalali, Ph.D., senior faculty at Vanderbilt University's School of Medicine, have been trying to reverse-engineer ketamine's mechanism of action for several ...

Allergan’s chief R&D officer David Nicholson, meanwhile, remains unfazed by the lingering uncertainty about the mechanism of action of ketamine-inspired drugs—as long as the drugs work.

New drugs to treat depression in particular are needed because many existing antidepressants don't work in up to 50% of ... The mechanism of action of the study drug provides insights into the ...

01.06.2022 13:02 New mechanism of ketamine’s antidepressant action Anna Hein Presse- und Öffentlichkeitsarbeit Max-Planck-Institut für Psychiatrie. Scientists could reveal part of the ...

Scientists have identified a novel mode of action for a potential antidepressant that also leads to nerve cell growth in the mouse hippocampus. The activator of a serotonin receptor uses a ...

An Israeli study has revealed that the mechanism of ketamine’s action on potassium channels in neurons may lead to improved therapies for depression. By JERUSALEM POST STAFF MAY 31, 2022 16:35 ...

The "Bipolar Disorder Market Analysis By Drug Class (Mood stabilizer, Anticonvulsant, Antipsychotic, Antidepressant, Antianxiety), By Mechanism of Action, By Region, And Segment Forecasts, 2014 ...

It is the only antidepressant whose sole mechanism of action is agonist activity at the 5- HT IA receptor. ... Cite this: Novel Depression Drug Hits Regulatory Roadblock - Medscape - Dec 03, 2015.

“Thank goodness we now have something with a different mechanism of action than previous antidepressants,” said Dr. Erick Turner, a former F.D.A. reviewer and an associate professor of ...

Researchers have reported progress in the important effort to explain the rapid antidepressant action of ketamine, and in so doing, have gained insights that may inform the development of other ...