Antibodies are a major component of adaptive immunity against invading pathogens. In this presentation, we will describe an analytical approach to characterize the antigen-specific antibody repertoire ...

The method utilises a “structure-to-sequence” computer algorithm ... used high-resolution cryo-EM to rapidly and precisely map where antibodies in rhesus macaque monkeys bind to synthetic ...

The protein language model is trained solely on paired human antibody sequences with scalable applications in antibody ...

At the core of their LENSai platform is a comprehensive and continuously expanding knowledge graph that maps 25 billion relationships across 660 million data objects, linking sequence, structure ...

the scientists first needed to map the route. They began by turning to an existing technology to sequence the collection of B-cell genes that code for all the antibodies created by a person's ...

It has been estimated that the human immune system can produce up to 1 quintillion different antibodies by changing the sequence of these amino acids, helping to ensure that the body can respond ...

However, this approach is not as successful in helping predict the structure of antibodies, since unlike most other protein sequences, antibodies are extremely variable. “The body makes billions ...

The sequence homology is over 95%; PTM and aggregation prediction reports are also available 100% success rate As quick as 3–4 weeks to offer required humanized antibodies Affinity evaluated by ...