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ahajournals.org4d
Conductance Artery Wall Layers and Their Respective Roles in the Clearance Functions
Although colliding circulating cells disperse potential energy within the arterial wall, the different layers counteract this effect: (1) the endothelium ensures a partial barrier function; (2) the ...
ahajournals.org4d
Elevated Blood Pressure in Transgenic Mice With Brain-Specific Expression of Human Angiotensinogen Driven by the Glial Fibrillary Acidic Protein Promoter
In addition to the circulatory renin (REN)–angiotensin system (RAS), a tissue RAS having an important role in cardiovascular function also exists in the central nervous system. In the brain, ...
Frontiers5d
Familial partial lipodystrophy resulting from loss-of-function PPARγ pathogenic variants: phenotypic, clinical, and genetic features
Other types of FPLD are caused by pathogenic variants in MFN2 and AKT2 genes (9). Autosomal dominant variants cause PPARG loss-of-function and consequent reduction in its receptor activity, leading to ...