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CRH-targeting drugs are predicted to lower cortisol in chronic stress and mood disorders. CRH-synthesis inhibitors and neutralizing antibodies are predicted to normalize all HPA hormones and glands ...

Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau proteins have been found in PDD, with intermediate changes for Aβ42 in non-demented PD. The authors investigated whether AD-related ...

How Hormones Impact the Belly There are a few hormones that can make things go awry with your abdomen. Changes in thyroid, sex, and stress hormones may cause belly problems. Fewer thyroid hormones ...

AD neuropathology is due to the progressive deposition of extracellular amyloid-beta (Aβ) peptide and intracellular hyperphosphorylated ... Aβ-induced neurodegeneration and associated ...

Background and aims: Psychological stress plays an important role in an array of intestinal disorders. Corticotrophin releasing hormone (CRH) is involved in the pathogenic process induced by ...

In individuals with Alzheimer's disease, a peptide known as amyloid-β accumulates and forms tangled plaques. People with diabetes have a higher probability of developing Alzheimer's disease ...

Major uncertainties remain about the impact of puberty blockers and gender affirming hormone therapy on children and young people with gender related distress (gender dysphoria), making it ...

Red 3—also called FD&C Red No. 3, erythrosine or E127—has been widely used in food, cosmetics and pharmaceuticals since its FDA approval in 1969. You've likely encountered Red 3 before. It's a ...

Maternal stress hormone levels during early pregnancy can have a lasting effect on the stress system of the offspring. The results of a long-term study on wild Assamese macaques in Thailand ...

Lee, T. H., Lerner, A. B., and Buettner-Janusch, V. (unpublished results). Li, C. H. (personal communication). Burgers, A. C. J., First Intern. Cong. Endocrinol. Abst ...

Multiple cellular changes are implicated in the disease process including amyloid beta and phosphorylation of tau synaptic ... environmental factors such as stress, vascular diseases, depression, ...