Here we hypothesized that the deletion of plasminogen and amiloride treatment protect against hypertension in diabetes mellitus. Impaired renal sodium excretion by plasmin–epithelial sodium channel ...

Correspondence to Professor Johan Sundström, Department of Medical Sciences, Uppsala Clinical Research Center, Uppsala 751 85, Sweden; johan.sundstrom{at}medsci.uu.se When a high-risk person is ...

We all have “blood pressure.” This simply refers to the way blood pushes against the walls of your arteries as your heart pumps. However, one in three American adults have a potentially dangerous ...

Amiloride achieved similar blood pressure control without the hormonal side effects linked to spironolactone, supporting its use as an alternative treatment option for resistant hypertension.

In this 6-week, double-blind trial, 585 patients were randomized to losartan/ hydrochlorothiazide or losartan as monotherapy and titrated as needed at 2-week intervals to reach goal blood pressure ...

Amiloride, a potassium-sparing diuretic, was noninferior to spironolactone in reducing home-measured systolic blood pressure (BP) after 12 weeks of treatment in patients with true resistant ...

Amiloride is noninferior to spironolactone in lowering home systolic blood pressure over 12 weeks in patients with resistant hypertension. The finding is from the SPironolactone Versus Amiloride ...

Noninferiority trial favored amiloride as an alternative to spironolactone in lowering home systolic blood pressure (SBP) for people with resistant hypertension. Twelve weeks into the trial ...

Amiloride is noninferior to spironolactone in lowering home-measured systolic blood pressure (SBP) among patients with resistant hypertension, according to results from a clinical trial published May ...

An alternative methodology by capillary zone electrophoresis (CZE) is proposed for the determination of losartan potassium (LOS) associated with chlorthalidone (CTD) or hydrochlorothiazide (HCT) in ...