For the first of these tasks Dr Baker and his colleagues use RF diffusion, an AI model they have developed to predict a ...

For the first time, chemists have discovered a unique way to control and modify a type of compound widely used in medicines, ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

What can a tiny wasp with a rather gruesome parasitic life cycle teach us about evolution, behavior and human developmental ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers ...

The gear was paid for with money from the American Rescue Plan Act, the COVID-aid stimulus package passed in 2021. "East Providence tries to lead the way in innovation," said DaSilva. "It brings ...

Kusminski, C.M. and Scherer, P.E. (2009) The Road from Discovery to Clinic Adiponectin as a Biomarker of Metabolic Status. Clinical Pharmacology & Therapeutics, 86, 592-595.

ATAD2 (ANCCA) is an epigenetic regulator and transcriptional cofactor, whose overexpression has been linked to the progress of various cancer types. Here, we report a DNA-encoded library screen ...

How to move and demolish structures at your base Now that we've covered how to get started with your base and some pointers about where to build it, let's talk about the mechanics of base building.

Using an algorithm they call the Krakencoder, researchers at Weill Cornell Medicine are a step closer to unraveling how the brain's wiring supports the way we think and act. The study, published ...

Determining accurate drug dissolution processes in the gastrointestinal tract is critical in drug discovery as dissolution profiles provide essential information for estimating the bioavailability of ...