Lipid kinases are enzymes that play a critical role in both cell signaling and membrane trafficking by phosphorylating lipid ...

Lipid kinases are enzymes that play a critical role in both cell signalling and membrane trafficking by phosphorylating lipid molecules in the body. The inhibition of two of these lipid kinases, ...

The ascidian Ciona (a genus of sea squirts) begins metamorphosis several tens of minutes after its larvae attach to rocks or ...

Moderate-quality evidence shows no differences in effects of adenosine and calcium channel antagonists for treatment of SVT on reverting to sinus rhythm, and low-quality evidence suggests no ...

Besides, among the theories about the mechanism of action of MTX, the primary anti-inflammatory action is attributable to adenosine release.

However, the exact mechanism that immune cells use to produce adenosine remained uncertain. To further examine this process, Nedbalova et al. – who are part of the research group that carried out the ...

ADENOSINE MECHANISM OF ACTION AND REGULATION The way adenosine regulates the immune system is through its bioavailability at the receptor site. 1 A good example is hypoxia or tissue ischemia ...

Scientists have discovered a mechanism called excitation-mitochondrial DNA transcription coupling (E-TCmito) that links neuronal activity to mitochondrial function. This mechanism plays a critical ...

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

Background Continuous intravenous administration of adenosine to humans often results in a paradoxical rise in pulmonary capillary wedge pressure (PCWP), whereas arterial resistance is lowered and ca ...

We therefore hypothesized that the response of atrial tachycardia to adenosine would be mechanism specific, with termination of atrial tachycardia due to sinus node reentry or cAMP-mediated triggered ...