P300 is an important and versatile coactivator common to many steroid receptors (Giordano ... cellular growth suggesting a key role for AR acetylation in prostate cellular growth control (Fu ...

CHARALAMPOUS and Hegsted 1 found that metabolic acetylation is impaired in experimental diabetes. They demonstrated this in alloxan-diabetic rats by the measurement of acetylated paraaminobenzoic ...

Acetylation is a chemical reaction that is called ethanoylation in the IUPAC nomenclature. It describes a reaction that introduces an acetyl functional group into a chemical compound. The opposite ...

This revealed a chemical modification, known as acetylation, which only occurs when the GR is bound to cortisol. However, this acetylation does not change the function of GR as a transcription ...

SIRT1 is a deacetylase, an enzyme that removes acetyl groups from proteins. Like phosphorylation, acetylation regulates many different cellular functions, including cytoskeleton dynamics.

Using an unbiased screen to look for changes in protein acetylation, the researchers profiled heart tissue from 5 end-stage heart failure patients who went on to receive heart transplants.

What drives one isoform to aggregate over the other? Post-translational modifications, namely acetylation, say researchers led by Markus Zweckstetter of the German Center for Neurodegenerative ...

The levels of H3K9 acetylation were examined at salt responsive gene promoter regions. They propose that, under normal condition, FVE/HDA13 complex acts at H3K9 for deacetylation, leading to low ...