This pathway, which is otherwise referred to as the AMPK-MNK-eIF4E axis, is a crucial aspect of selective protein translation that occurs during ketogenic states like fasting.

Credit: Shutterstock. PXL770 is a novel, first-in-class direct adenosine monophosphate-activated protein kinase (AMPK) activator. The Food and Drug Administration (FDA) has granted Fast Track ...

A new systematic review reveals that rapamycin – a compound originally developed as an immunosuppressant – can deliver ...

The metabolic protein AMPK has been described as a kind of magic bullet for health. Studies in animal models have shown that compounds that activate the protein have health-promoting effects to ...

Intermittent fasting shows promise in enhancing cognitive function and supporting brain health, with implications for neurodegenerative disease research. ... (AMPK) and sirtuin 1 (SIRT1) ...

One of the main functions is activating an important enzyme called AMPK, ... In a 2008 study of 116 people with diabetes, taking 1 gram of berberine per day lowered fasting blood sugar by 20% .

Intermittent fasting improves multiple indicators of cardiovascular health in animals and humans, including blood pressure; resting heart rate; levels of high-density and low-density lipoprotein ...