Hannah Mai, 37, from Coventry, gained 10st (6.3kg) because of a rare hormonal disorder - but credits one daily exercise for ...

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While endogenous Cushing's syndrome can be caused by an adrenocorticotrophic hormone (ACTH)-dependent or ACTH-independent mechanism, it is most often a result of excess secretion of ACTH by a ...

Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX) today announced that on June 10, 2025, the Compensation Committee of the Board ...

Graves' disease and thyroid eye disease (TED) - TSH antagonist Autosomal polycystic kidney disease (ADPKD) - SST3 agonist A live question-and-answer session will follow the formal presentations. To ...

Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX) today announced that on June 10, 2025, the Compensation Committee of the Board of Directors granted non-qualified ...

Tumours that secrete adrenocorticotropic hormone (ACTH) can overstimulate cortisol release and result in Cushing's syndrome. These tumours may be benign or malignant and are frequently located in ...

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Introduction: ACTH-dependent Cushing syndrome (CS) is a rare endocrine disease including Cushing disease (CD), ectopic ACTH syndrome (EAS) and ectopic corticotropin-releasing hormone (CRH) syndrome.

Cushing (1869-1939). The recognition that glucocorticoid excess ... pressure despite blockade of cortisol-induced hyperinsulinemia. In experimental studies of ACTH-induced hypertension in the rat ...