Stefano Biondi. I reviewed the available biological data and decided that the compound had clinical potential against clinically relevant Gram-negative pathogens, and proposed pairing it with the ...

Letter from Congresswoman Slaughter to the Food and Drug Administration (FDA) over possible approval of fourth-generation cephalosporins for use in animal agriculture, despite the recent conclusion by ...

In the multi-center, cluster-randomized crossover study, the researchers randomly assigned eight European ICUs to two 9-month intervention periods in which they could use one of three antibiotic ...

(4) Cefepime/Enmetazobactam - Pharmacological Edge: Cefepime/enmetazobactam is a combination of cefepime, a well-known fourth-generation cephalosporin, and enmetazobactam, a novel β-lactamase ...

The company said the fourth-generation reactor would supply both heat and electricity and would include advanced safety features. CNNC also said it received approval for two Hualong One reactors ...

The combination of enmetazobactam — invented by scientists associated with Chennai-based pharma firm Orchid Pharma in 2008 — and cefipime, a fourth generation cephalosporin antibiotic, is used in ...

Enmetazobactam, in combination with the fourth-generation cephalosporin antibiotic Cefepime, has been proven to overcome antimicrobial resistance produced by extended-spectrum beta-lactamase-producing ...

The intravenous formulation is a fixed-dose combination of enmetazobactam – a novel extended-spectrum-lactamase inhibitor belonging to the penicillanic acid sulfone class – with the 4th generation ...

Exblifep is a combination of cefepime, a fourth-generation cephalosporin, and enmetazobactam, a novel extended-spectrum beta-lactamase inhibitor. Cefepime exerts bactericidal activity by ...

During the same period, sales of antibiotic classes that are considered critically important in human medicine for veterinary use noticeably decreased: sales of third- and fourth-generation ...