we've uncovered the most common fault in DNA replication by far, which we didn't even start out looking for! More surprising still is that a single enzyme is so crucial to repairing over a million ...

Researchers have discovered an enzyme ... with DNA damage, such as cancer and neurodegenerative diseases. Fortunately, the body has a natural way of repairing DNA harmed through the replication ...

Loss of TLK1 and TLK2 results in extensive DNA damage during DNA replication ... identified a key role for the TLK1 and TLK2 enzymes in DNA replication. "We demonstrated that TLK activity is ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind ...

Figure 4: Architecture of the replicative ... by DNA topoisomerase I. After full replication, the two DNA strands are separated by DNA topoisomerase II. Enzymes that digest DNA can be divided ...

The DNA double helix is made from two strands that run in opposite directions. Each strand is made of a series of bases, A, T, C and G, that pair up between the strands: A to T and C to G. The first ...

In this study we show that most chromatin-modifying enzymes ... Figure 4: Heterochromatin proteins are found in proximity to nascent DNA in defined order following replication.

Rather than wait for highly accurate DNA polymerase enzymes, the cell may call on ... yeast cells produce far more replication errors than would have been expected. These errors, which occurred ...

During cell growth, cells copy their DNA through a process called DNA ... have identified a key role for the TLK1 and TLK2 enzymes in DNA replication. "We demonstrated that TLK activity is ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications ...