Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the ...

However, the 3D structure of ABCC4 and the molecular mechanism of its broad-spectrum substrate transportation remain unknown. Using cryo-electron microscopy, the researchers obtained the 3D ...

Cisplatin has been used as a treatment for cancer since its approval by the US Food and Drug Administration in 1978. And while five other platinum drugs based on the structure of cisplatin have ...