Researchers assembled the genome and 3D chromosomal structures of ... Mapping the woolly mammoth’s DNA was almost like solving a puzzle with “three billion pieces,” corresponding author ...

Building off work mapping the 3D structure of ... you start putting the puzzle pieces together." Then, they combined the physical information from the Hi-C analysis with DNA sequencing to identify ...

Like trying to put together a puzzle with missing pieces ... But they can’t capture large-scale differences at the chromosomal level. Because DNA relies on the chromosome’s 3D structure to function, ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

a class of complex DNA amplicons. These results rigorously link genome-wide high-order 3D interactions to lineage-defining transcriptional programs and establish Pore-C and Chromunity as scalable ...

The next step was to find out its structure and Cambridge scientists Francis Crick and Watson were trying to build a 3D model of the DNA molecule. They were competing with a team at King’s ...

Described December 23 in the journal Science Advances, the software lets users take drawings or digital models of rounded shapes and turn them into 3D structures made of DNA. The DNA ...

Using data that she had presented, Watson and Crick had tried building a model to puzzle out DNA’s structure. But after Franklin’s department chair lodged an outraged protest, Watson and Crick ...

Researchers of the 3D-BRICKS project want to focus on the use of Carbon Nanotubes - the most promising candidates because of their nano dimensions - together with DNA technologies, to obtain nano ...

A new study by Weill Cornell Medicine investigators reveals that beyond providing a convenient way to store DNA in a tight space, the 3D organization of noncoding gene regulators in chromatin ...

The first crystal structure of an alternative DNA shape from the insulin gene has ... because when scientists know the specific 3D shape, they can design molecules digitally and model them to ...