Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is common for most RNA strands, it forms a closed loop. Known as circular RNAs ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

In detail, we tried to understand if TTMD can be used as a post-docking filter to steer the identification of a native-like binding pose for small organic ligands onto RNA receptor binding sites.

Freeze–thaw cycles in an icy pond could let an enzyme copy RNA double helices indefinitely — suggesting one way in which ...

In 2012, scientists Jennifer Doudna and Emmanuelle Charpentier replicated this mechanism found in microbes to develop a ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Here we present HyperFold, a multistrand RNA/DNA structure prediction approach for predicting ... of a two-stranded RNA molecular switch that upon binding to a single-stranded RNA toehold ...

In biomimetic nanotechnology, one aims to construct complex, nanoscale supramolecular structures ... avenue for tecto-RNA because of the programmability of Watson−Crick basepairing and the ...