Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers
In a recent study, precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS ...
News-Medical.Net on MSN3d
FGFR2 identified as key driver in KRAS-mutated pancreatic cancer progression
Precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had ...
Pancreatic cells 'remember' cancer-linked epigenetic marks without mutations, study shows
Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between ...
GEN - Genetic Engineering and Biotechnology News3d
Inhibiting FGFR2 Supports Prevention and Delay of Common Pancreatic Cancer
Results showed that FGFR2 gene deletion led to significantly fewer precancerous lesions and delayed PDAC tumor formation ...
Science Daily1d
Pancreatic cells 'remember' epigenetic precancerous marks without genetic sequence mutations
Scientists say they have found a pattern of so-called epigenetic 'marks' in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a ...
Science Daily3d
In pancreatic cancer, a race against time
Scientists have found a way to 'intercept' pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to ...
Medical Xpress on MSN15d
Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer: Study
Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept ...
Medical Xpress on MSN17d
Genetic Mutation Predicts Pancreatic Cancer Metastasis
"Historically, we've known that KRAS mutations are associated with a more biologically aggressive pancreatic cancer," says Jennifer Leiting, M.D., hepatobiliary and pancreatic surgeon within Mayo ...