have analyzed global changes in mRNA length in a murine model of atherosclerosis progression. They observed variations in the 5'UTR, 3'UTR, and coding regions of mRNAs, which become shorter as ...

Shah and colleagues take advantage of the presence of maternal and somatic ribosomes in zebrafish and confirm their differential expression during development. The authors convincingly show that ...

These longer 3′ UTRs tend to remain in the neuronal soma, whereas shorter UTR isoforms localize to the synapse. In cultured pumilio mutant neurons, axon outgrowth defects are accompanied by mRNA ...

Although we know that a microRNA can exert effects on mRNA stability and/or protein synthesis, we do not yet understand what features of the interaction and what associated factors determine the ...

This valuable study combines massively parallel reporter assays and regression analysis to identify sequence features in untranslated regions contributing to the stability of in vitro transcribed mRNA ...

Feb. 14—A bill that would ban the use of mRNA vaccines, including for Covid-19, is on its way to the House floor after passing out of committee in a party-line vote Wednesday. Sponsored by Rep.

The findings, in mouse models and isolated human brain tissue, were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the ...

Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system. Nature Materials , 2025; DOI: 10.1038/s41563-024-02114-5 Cite This Page : ...