The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

mRNA-based therapies Historically, production costs for mRNA therapies have been high, stability has been poor, and products have been associated with high immunogenicity. However, new strategies in ...

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component ...

No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

mRNA modifications like m 5 C are typically introduced by tRNA-modifying enzymes, while the catalytic mechanism and function remain debated.

The Hong Kong-listed firm is advancing its pipeline using an mRNA system it says can compete with the industry’s best.

The mRNA therapeutics field is rapidly evolving beyond vaccines to include treatments for cancer, genetic disorders and in vivo cell therapies, bringing with it diverse production challenges. As the ...

Scientists at Tel Aviv University and the Israel Institute for Biological Research have developed the first mRNA vaccine proven completely effective against deadly bacteria. This groundbreaking ...

This study expands the understanding of the complex regulatory networks that govern protein synthesis and underscores the critical role of mRNA modifications in fine-tuning essential cellular ...

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component ...

Plant scientists have used a standard "gene gun" since 1988 to genetically modify crops for better yield, nutrition, pest resistance and other valuable traits.