Researchers at NYU Abu Dhabi discovered how m6A methylation controls the production of essential proteins in neurons, crucial ...

Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered ...

A team of researchers at NYU Abu Dhabi has uncovered a key mechanism that helps shape how our brains are wired, and what can ...

A team of researchers at NYU Abu Dhabi has uncovered a key mechanism that helps shape how our brains are wired, and ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

Oncotelic Therapeutics, Inc. (OTCQB: OTLC) ("Oncotelic" or the "Company"), a clinical-stage biopharmaceutical company focused on RNA-based therapeutics, today announced the publication of a ...

Drs Olga Brieieva and Martin Higgs discuss in vitro genomic models for predicting clinical resistance to PARP inhibitors for ...

Despite having identical genetic instructions, female honey bee larvae can develop into either long-lived reproductive queens ...

Methylation of nitrogen 6 in the adenosine ring, or m 6 A, is the most common chemical change cells make to their own mRNA. The modification can be both physiological and pathological, and bulk ...

A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis, Science 2021; 371 (6525):145-153.

Therefore, we hypothesized that LRPPRC mRNA may be a target of BCDIN3D-mediated methylation. Unfortunately, there is no available antibody to enrich 5′-Pme-modified RNAs, and mass spectrometry and ...

Conclusion: We observed that increased FN mRNA (m6A) methylation enhanced cardiac fibrosis following MI. Inhibition of mRNA methylation using STM2457 in in-vivo, and siRNA in-vitro reduced ...