and lacked the integrationof DNA methylation with mRNA expression data to fully reveal the pathophysiological contributions and the functional roles of DNA methylation in RA. As DNA methylation plays ...

F-box protein 43 methylation and mRNA levels in PBMCs were detected by MethyLight and quantitative real-time PCR. Conclusion: Hypomethylation of the F-box protein 43 promoter in PBMCs is a promising ...

Although the three assays had different levels of sensitivity, we believe that the consistent results from different methodology and biological validation at DNA methylation level and mRNA expression ...

In this study, we for the first time have integrated various Rb microarray NCBI-GEO datasets including DNA Methylation (GSE57362), miRNA (GSE7072) and mRNA (GSE110811) to comprehensively investigate ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

Therefore, the aim of this study was to investigate the pro-fibrotic impact of hypoxia on cardiac fibroblasts, and determine whether alterations in DNA methylation could play ... and α-smooth muscle ...

There have been 67 confirmed human bird flu cases in the U.S. since April 2024. Moderna has been awarded approximately $590 million from the federal government to help speed up the development of ...

Moderna (NASDAQ:MRNA) was among the notable gainers on Wednesday after Oracle (NYSE:ORCL) Chairman Larry Ellison highlighted the AI's potential in the development of messenger RNA-based cancer ...

Oracle Chairman Larry Ellison highlighted the potential medical benefits of the investment, stating that AI could be used to detect cancers and customize mRNA vaccines to treat them within 48 hours.

Occasionally, these molecular decoders pause on the mRNA, either because they are instructed to do so or they have difficulty traversing the sequence. Previous studies that investigated these events ...