Human metapneumovirus (HMPV) has been visualized by electron microscopy, ... The Fprotein mediates the fusion of the host cell membrane and virus envelope during the initial stages of virus entry.

It consists of two distinct mRNA sequences encoding the membrane fusion (F) proteins of hMPV and PIV3 formulated in Moderna’s proprietary lipid nanoparticle (LNP) technology. mRNA-1653 is wholly ...

They can lead to lesser known symptoms of hMPV: It may lead to conjunctivitis, which is the inflammation of the conjunctiva, a thin membrane that protects the eye. It can lead to red, itchy ...

Subscribe for FREE Scientists have long attempted to create vaccines that coax the immune system into recognizing the fusion (F) proteins present on the surfaces of RSV, hMPV and related viruses.

We analyzed 64 human metapneumovirus strains from eight countries. Phylogenetic analysis identified two groups (A and B, amino acid identity 93% 96%) and four subgroups. Although group A strains ...

EDP-323, a novel non-nucleoside RSV L-inhibitor, and EDP-938, a non-fusion RSV replication inhibitor, were evaluated against RSV-A and -B isolates in a 3D pseudostratified epithelium (EpiAirway ...

Last spring, McLellan's team described having developed a way to lock this fusion protein into its prefusion conformation, which is useful for a vaccine. In a paper out this week in Cell Reports , ...

Hologic, Inc. HOLX announced the receipt of 510(k) clearance from the FDA for its Panther Fusion AdV/hMPV/RV assay. This is a multiplex assay that.