DelveInsight’s c-MET-NSCLC pipeline report depicts a robust space with 20+ active players working to develop 20+ pipeline ...

D tumoroid models transform cancer research, accurately reflecting tumor biology and enabling effective drug testing and ...

In addition, HER2 activation can activate Ras/Raf and MEK pathways, which favors cancer cells’ growth and migration. Trastuzumab has been proposed to trigger HER2 internalization and degradation ...

Data from the Phase 3 PALOMA-3 study showed non-inferiority to intravenous administration meeting both co-primary pharmacokinetic (PK) endpoints, as well as a five-fold reduction in infusion-related ...

and novel agents (e.g. tirapazamine, EGFR inhibitors and other targeted agents) with radiotherapy will be examined. This article is part one of two articles. In the subsequent article, the general ...

1Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China. 2Benxi Institute of Pharmaceutical Research, Shenyang Pharmaceutical University, Benxi, China. Search for other works ...

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

One such strategy is to repurpose FDA-approved kinase inhibitors that are potential chemotherapeutic ... but inhibition of the JAK pathway may potentially be used to limit SARS-CoV-2 infection.

L-tyrosine is taking off as “liquid Adderall” within the ADHD community on TikTok. Some social media creators are touting it as a “natural” alternative to prescription medications, while others prefer ...

Consecration and 10 steps to cleansing. They do dovetail with our responsibilities. What is required of a priest and how does the priesthood parallel with those who are Christians? Can you draw a ...