Before their translocation in 2015, black rhinos hadn’t been seen in Samburu since the late 1980s, according to Albert Leturuka, Sera Rhino Sanctuary Manager. Historically, black rhinos roamed ...

ALX2004 is a potential best- and first-in-class antibody-drug conjugate (ADC) for the treatment of EGFR-expressing solid tumors that was created from ALX Oncology’s proprietary linker-payload ...

The FDA has cleared the investigational new drug (IND) application for ALX2004 for the treatment of epidermal growth factor receptor (EGFR)-expressing solid tumors. ALX2004 is a first-in-class ...

In mammalian cells, recombination between Alu sequences generates intrachromosomal deletions and translocations; several such rearrangements are associated with leukemias (Jeffs, et al., 1998; Strout ...

Tagrisso significantly improves overall survival in unresectable stage 3 EGFR-mutant NSCLC, surpassing placebo in the LAURA study. The FDA approved Tagrisso in September 2024 for patients with locally ...

Laboratory of Nanoscale Biology (LBEN), Institute of Bioengineering, School of Engineering, Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland ...

Osimertinib monotherapy and combination treatment had safety profiles consistent with previous data on use of the drug in EGFR-mutated NSCLC. Osimertinib (Tagrisso) displayed a sustained overall ...