Previous reports have shown that EGFR translocation to the nucleus is associated with cell proliferation. Here we investigated mechanisms of acquired resistance to cetuximab using a model derived ...

EGFR as a molecular target has yet to be individualized for ... AKT activation is initiated by translocation to the plasma membrane. AKT phosphorylation is carried out by 3-phosphoinositide-dependent ...

EGFR, epidermal growth factor receptor, is a protein found on the surface of your cells that makes them grow. If you have non-small-cell lung cancer (NSCLC), your cancer might carry certain ...

A schematic diagram showing the significant contribution of SCoV2-induced altered mitochondrial dynamics and mitochondrial EGFR translocation in sustaining viral propagation. First, SCOV2 RNA and ...

The researchers found that treatment with the medicine finasteride was related with increased EGFR nuclear translocation, but in men treated with finasteride plus ERβ agonist, isoflavone ...

If you have EGFR-positive lung cancer, you have some choices to make about treatment options. Especially if your cancer is advanced. Your doctors can help you choose from a list of approved drugs ...

They found both previously known and novel mutations significantly linked to EGFR activation and drug response, demonstrating the method's precision and revealing new pathways affecting tumor ...

Please provide your email address to receive an email when new articles are posted on . Newer eGFR calculations that do not consider race show a link between kidney function and dementia.

Declines in eGFR after transition to sacubitril/valsartan for HF are mild and temporary. Image: Adobe Stock “Moreover, although some of these drugs have demonstrated renal protective effects ...

A novel topical formulation of a BRAF inhibitor significantly reduced acneiform rash associated with anti–epidermal growth factor receptor (EGFR) therapies in patients with colorectal cancer ...

They also discovered that the virus manipulates the EGFR protein, which is critical for cellular growth signaling, to maintain this rapid replication. This increases the likelihood of the virus ...