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The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...
A Growing Double BurdenThe rising prevalence of prediabetes and chronic kidney disease (CKD) in India reflects an ...
Communication between these different cell types, also called paracrine signaling, is essential for normal cardiac function, but also important in cardiac remodeling and heart failure. Systematic ...
CHICAGO – Circulating tumor DNA testing may improve outcomes for colorectal cancer patients retreated with anti-EGFR therapies after they stop responding initially, according to data presented at the ...
Discovery of Novel Epidermal Growth Factor Receptor (EGFR) Inhibitors Using Computational Approaches
State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China ...
This manuscript focuses on developing a structural model of how the multidomain ECM protein SVEP1 enables Angiopoietin (ANG) binding to the orphan receptor TIE1, resulting in downstream receptor ...
SVEP1 enables efficient binding of Angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling Katharina Uphoff Melina Hußmann Dörte Schulte-Ostermann Yvonne ...
Department of Infectious Diseases, Medical Research Institute, Zhongnan Hospital of Wuhan University; Frontier Science Center for Immunology and Metabolism, Taikang Center for Life and Medical ...
Creative Biolabs recently updated its antibody chip platform, expanding product arrays for phosphorylation signaling and cytokine detection. SHIRLEY, NY, UNITED STATES, May 27, 2025 /EINPresswire.com/ ...
the targeted blockade of the EGFR signaling pathway - even in the presence of a KRAS mutation. This could make KRAS-mutated colon cancer more treatable than previously thought. Our results show ...
The downstream chromatography industry is at the forefront of bioprocessing innovation, driving advancements in the purification and production of biopharmaceuticals. This eBook delves into the ...
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