Also, resistant cells can harbor activating mutations in PI3K or Akt, which can trigger other downstream signaling pathways even when HER2 ... cyclin-dependent kinase 2; EGFR, epidermal growth factor ...

Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...

EGFR, epithelial growth factor receptor; MMP-2, matrix metalloproteinase-2; MMPs, matrix metalloproteinases; TGN, trans-Golgi-network; GSK-3β, glycogen synthase kinase-3β; MAVS, mitochondrial ...

Clin Colorectal Cancer. 2009;8(1):15-21. The primary toxicity of oxaliplatin is neurotoxicity, which exists as an acute, unique, cold-related neuropathy as well as a cumulative peripheral ...

There are several known downstream targets of S1PR1 signaling which may be active in MG after retinal damage. To identify second messenger pathways that were affected by diminished levels of S1P in ...