Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology in ...

In this week’s Science for All newsletter, Manaswini Vijayakumar breaks down an experiment that allowed scientists to see the ...

In this week’s Science for All newsletter, Manaswini Vijayakumar breaks down an experiment that allowed scientists to see the ...

This process tethered the target molecules to the magnetic beads, and the magnetic beads to the grid. With the particles securely in place, blotting could then be done safely, with far less sample ...

and the magnetic beads to the grid. With the particles securely in place, blotting could then be done safely, with far less sample loss. "In traditional cryo-EM, the target molecules just float ...

and the magnetic beads to the grid. With the particles securely in place, blotting could then be done safely, with far less sample loss. “In traditional cryo-EM, the target molecules just float ...

The chromatin droplet solution was applied to the back side of the cryo-EM grid and rapidly vitrified using a highpressure freezer. The grid was then imaged with a cryo-fluorescence microscope to ...

“Future grid failures could have even more severe consequences,” she added. The widespread outage raises questions about the resilience of the power infrastructure in Spain and Portugal ...

(A) The on-bead-cryo-EM approach reduces preparation steps (for example, target isolation, enrichment, and buffer exchange), which can lead to sample loss. (B) Sample loss during the grid-freezing ...

The researchers then used a strong magnet to attract the magnetic beads to the cryo-EM grid membrane, which enabled them to generate sufficient cryo-EM data from a dilute sample. The MagIC-cryo-EM ...