What are the early symptoms of lupus? There is no one first sign or symptom of lupus. The early signs and symptoms of lupus are generally the same as the symptoms of lupus, including extreme fatigue, ...

Skin rashes: A hallmark of lupus is a facial rash often described as a "butterfly rash" across the cheeks and nose.

Patients with systemic lupus erythematosus with a history of cutaneous lupus erythematosus are more likely to have high ...