Scientists at Washington University School of Medicine in St. Louis have identified a protein essential to repairing the intestine's inner lining. "For example, inflammatory bowel disease can ...

It has been previously demonstrated that the WNT gene/protein family member WNT5A is down-regulated in leukemia, and low expression of this tumor suppressor has been correlated with disease ...

Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression. Nature Communications , 2025; 16 (1) DOI: 10.1038/s41467-025-58748-9 Cite This Page : ...

Wnt3a, Wnt5a, Wnt7b, Sfrp4, ... Intestinal stem cells (ISCs) constitute a small proportion of intestinal epithelium and are defined by demonstrating a self-renewal capacity and multipotency.

Wnt5a can activate Rho GTPases in chronic lymphocytic leukemia (CLL) cells by inducing the recruitment of ARHGEF2 to ROR1. Mass spectrometry on immune precipitates of Wnt5a-activated ROR1 ...

WNT5A was hypomethylated in 11/17 (65%) tumors, S100P in 8/16 (50%) and CRIP1 ... Lee-Ambrose LM, Cousins RJ . (1993). Regulation of cysteine-rich intestinal protein by dexamethasone in the ...

More information: Kamrul Hasan et al, Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway, Oncotarget (2023). DOI: 10.18632/oncotarget.28386 Journal information: Oncotarget ...

Wnt5a gene expression in squamous cell carcinoma was significantly higher than that in adenocarcinoma (P < .0001). There was a significant correlation between the normalized Wnt5a gene expression ...

From gliders to bats. We discovered that levels of a gene called Wnt5a are strongly correlated with the onset of those early skin changes – condensation and hyperplasia.

Intestinal Wnt2 expression at the protein level was also found to be increased in germfree mice colonized with S. typhimurium compared with control. ... Wif1, Wnt5a, Wnt8b, Fzd3, ...