Lactase is encoded by a single gene (LCT) of approximately 50 kb located on chromosome 2. The gene has 17 exons and codes for an mRNA molecule which has 6274 bases with 1927 amino acid residues. ...

In this interview, we speak to Professor Mark Thomas about his latest research into lactase persistence and how it has evolved over the years. My name is Mark Thomas, and I am a professor of ...

This happens when the small intestine doesn't produce enough lactase, the enzyme needed to break down lactose. While the enzyme increases as we grow, it is produced in large quantities the body ...

Lactose intolerance occurs when a person's body produces only a small amount of lactase. Lactase is naturally produced by cells arranged and bacteria living in the small intestine. People in need of ...

Why would this be? First, it is necessary to understand that ”milk intolerance” is generally caused by a deficiency in lactase–an enzyme found in the small intestine of almost all mammals at ...

Until 8,000 years ago, humans were only able to digest lactose, a form of sugar present in fresh milk, during childhood because as adults they lost the ability to produce endogenous lactase ...

Evidence of Still-Ongoing Convergence Evolution of the Lactase Persistence T-13910 Alleles in Humans: A single-nucleotide variant, C/T-13910, located 14 kb upstream of the lactase gene (LCT), has been ...