Antibiotics that target bacterial cell wall synthesis: β-Lactams (usually given with a β-Lactamase inhibitors to prevent the bacteria from inactivating the beta-lactam ring of the antibiotic ...

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Surgical patients with a documented beta-lactam allergy were nine times less likely to receive the preferred first-line antibiotic cefazolin but more likely to receive riskier, alternative ...

Infants of mothers treated in the first trimester with TMP-SMX appeared to have a higher risk for any malformation than those ...

Rapid molecular diagnostics platforms may be a valuable tool in guiding beta-lactam antibiotic treatment decisions, particularly in cases where beta-lactamase genes are not identified and the rate ...

Beta-lactam antibiotics kill many bacteria by inactivating proteins involved in cell wall synthesis. But MRSA bypasses the drug's actions by stimulating a gene called mecA, which in turn activates ...

The previously largest randomized trial to date, counting 432 people, had shown continuous infusion of beta-lactam antibiotics to make no difference for 90-day mortality in severe sepsis (26% vs ...

Bacteria can produce enzymes that make them resistant to antibiotics; one example is the TEM beta-lactamase enzyme, which enables bacteria to develop a resistance to beta-lactam antibiotics, such ...

“What’s interesting is that beta-lactamases are actually a major cause of antibiotic resistance as they destroy beta-lactam antibiotics, which are some of our most commonly prescribed ...

Confirming Allergies Will Improve Care "We are in a place right now where understanding beta lactam antibiotic allergies is very important, because they are such a large number of antibiotics, and ...