What Are Antimetabolites, and How Do They Work? Antimetabolites are called a “cytotoxic” type of drug because they kill cells. They work by mimicking the molecules that a cell needs to grow.

Antimetabolites are a type of chemotherapy drug that mimics molecules that cancer cells need to create their DNA. Learn more about this cancer treatment.

Chemotherapy drugs can kill cancerous cells through several mechanisms. There are many types of chemotherapy drugs, including alkylating agents and antimetabolites. Chemotherapy drugs are unable ...

IN the early 1950's a team of chemists directed by George Hitchings undertook a new approach to the design and synthesis of antimetabolites that might inhibit neoplastic growth. Working from what w ...

The first attempts to control autoimmune disease by other than surgical therapy included the use of chemicals, such as urethane and nitrogen mustard, that had been demonstrated to suppress ...

The halogenated thymidine analogs, 5-bromo-2′-deoxyuridine (BrdUrd) and 5-iodo-2′-deoxyuridine (IdUrd) were among the first antimetabolites shown to enhance ionizing radiation-induced cell killing ...