Multiple pathways, such as the intrinsic pathway ... Major therapies for clotting disorders – warfarin and clopidogrel – are currently at the forefront of clinical studies for evaluation ...

Attention should be paid to the relative importance of the warfarin cytochrome P450 (CYP) metabolic pathways. Warfarin is a racemic mixture of its R-isomer (less potent) and S-isomer (more potent).

Pancreatic carcinoma is associated with thromboembolism, caused by increased levels of coagulation factors and decreased thrombolysis. Warfarin prolongs survival and improves the response to ...