As shown in Figure 4, the odds of vortioxetine treated patients achieving a ≥50% MADRS score reduction from baseline was about 3 times higher than placebo treated patients (Overall OR = 2.87 ...

Withdrawal symptoms can vary depending on the antidepressant, and strategies for tapering off the medication may help.

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Takeda Pharmaceuticals and Lundbeck have jointly announced the submission of a New Drug Application (NDA) to the US FDA for the investigational agent vortioxetine. Vortioxetine (Lu AA21004 ...

flexible-dose vortioxetine: A pilot study," highlights the application of EEG in monitoring cognitive changes during treatment for MDD. Key findings include: BNA™ Metrics as Cognitive Biomarkers ...

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The company is also facing patent expiries for its antidepressant Trintellix/Brintellix (vortioxetine) – for many years its biggest-selling drug – in 2026, while its new top product Rexulti ...

In the 1970s, Masters and Johnson reported that vaginismus could be easily treated with behaviorally oriented sex therapy that included vaginal dilatation. [3] The first step of their treatment ...

Mental health includes our emotional, psychological, and social well-being. It affects how we think, feel, and act, and determines how we handle stress and make choices. Emotional sobriety is less ...