An obscure group of phages offers insights into elements of microbial warfare—and blueprints for new antibiotics.

During cell-to-cell spread, HIV-1 protease activity triggers CARD8 inflammasome activation and IL-1β release from macrophages, which may contribute to inflammation and chronic immune activation.

Influenza virus is internalized via receptor-mediated endocytosis and then fuses with the endosomal membrane at low pH. Hemagglutinin, a glycoprotein found on the surface of influenza virus, is ...

About 30% of all respiratory tract infections are caused by coronaviruses, leading to widespread illnesses and, in some cases ...

Multidisciplinary AI- and physics-driven modeling of the viral fusion process has enabled the discovery of an orally available drug inhibiting infection with multiple coronaviruses.

About 30% of all respiratory tract infections are caused by coronaviruses, leading to widespread illnesses and, in some cases ...

Scientists have discovered a unique class of small antibodies that are strongly protective against a wide range of SARS ...

Even though NAbs primarily work by neutralizing viral antigens, on some occasions, they may also combat the SARS-CoV-2 virus escaping neutralization by employing several effector mechanisms in ...

Syncytium—the establishment of persistent infection via formation of syncytia. In the ongoing saga of long COVID-19, one compelling theory points to persistent viral reservoirs lurking in certain ...

Influenza A virus envelop protein hemagglutinin (HA) plays important roles in viral entry. We previously have reported that MBX2546, a novel influenza A virus inhibitor, binds to HA and inhibits ...