After nuclease cleavage, DSBs can be repaired by non-homologous end joining (NHEJ ... However, the expression of dCas9-CtIP is not sufficient by itself to stimulate integration. In addition, the ...

Enhancement of viral receptor expression: Upregulating genes related to viral vector infection ... associated with random integration by traditional viral vectors. For example, in some studies, CRISPR ...

Google announced at Google I/O 2025 on Tuesday that it’s launching a Gemini integration in Chrome. The tech giant says the new integration will give users access to a new AI browsing assistant ...

† Department of Radiation and Cellular Oncology, University of Chicago, 5758 S. Maryland Avenue, Chicago, Illinois 60637, United States ‡ Department of Medicinal Chemistry and Pharmacognosy, Drug ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. AAVPureMfg produces high-purity AAV vectors ...

As its exonuclease activity is essential for homologous recombination (HR) and replication fork processing, EXO1 has emerged as a compelling therapeutic target, especially in cancers marked by ...

Safety and Activity of Fibroblast Growth Factor Receptor Inhibitors in Advanced Malignancies: A Pooled Analysis of Early-Phase Clinical Trials Fourteen patients were accrued to the trial, which was ...

1Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland.

Abstract: To the ambiguous question of data from multi-souce sources vector map, the paper described the overall framework, content and methods of data integration and fusion. Data integration ...

However, managing power transfer between the energy storage systems and motor poses a challenge. To address this, a multi-objective vector modulation strategy is introduced. This strategy aims to ...