Our previous work5 and others’ indicate that vector preparations are typically contaminated with varying amounts of wild-type virus when standard methods of homologous recombination between ...

Researchers have revealed the fundamental mechanisms underlying homologous recombination – one of the main DNA repair pathways in human cells.

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

“While Google is a relatively late entrant, it brings formidable strengths — a native cloud-first architecture, deep Workspace integration, and powerful foundation models via Gemini,” said ...

gretroviral and lentiviral vectors with a vector-specific nonrandom integration pattern in target cell genomes as revealed by integration analysis. Further optimization is needed for reduction of ...

The ASEAN-5 region, which comprises Indonesia, Malaysia, the Philippines, Singapore, and Thailand, has benefited substantially from its integration to the world economy, particularly through trade.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. AAVPureMfg produces high-purity AAV vectors ...

Working Papers describe research in progress by the author(s) and are published to elicit comments and to further debate In this paper, we derive evidence on the integration of international stock ...