Notable reduction in illegitimate integration mediated by a PPT-deleted, nonintegrating lentiviral vector. Mol Ther 2011; 19 : 547–556. Article CAS PubMed Google Scholar ...

Gene Therapy - Vector integration: Pest not guest. In a recent study, published in Cell, Frederic Bushman and co-workers 2 mapped HIV type 1 (HIV-1) integration sites in the human genome. Bushman ...

The researchers analyzed more than 280,000 vector integration sites (VIS) from 10 patients with X-linked severe combined immunodeficiency (SCID-X1), also known colloquially as “bubble boy ...

Redis has had vector search capabilities in its platform before, but with the growth of AI in 2023, there has been a spike in interest across the company’s user base.

The risk of second tumors after chimeric antigen receptor (CAR) T-cell therapy, especially the risk of T-cell neoplasms related to viral vector integration, is an emerging concern. A total of 724 ...