Samples corresponding to colorectal cancer cases were obtained from the Ontario Tumor Bank (Ontario Institute for Cancer Research, ON, Canada), BC Cancer Agency (Vancouver, BC, Canada) and St Paul ...

describe a novel metabolic ‘safety switch’ based on the disruption of uridine monophosphate synthetase (UMPS) — an enzyme that catalyses the biosynthesis of the nucleotide UMP — and ...

In the long term, uridine could be a potential target for therapeutics against eating disorders in humans. Uridine is known primarily as a precursor for RNA, but also plays a central role in many ...