Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

The company, which secured $200 million from investors in a private funding deal last week, learned Tuesday of a serious side effect experienced by one participant on a high dose of its Rett therapy.

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from ...

Not all stressors have the same impact on health. Stress arising from threats to social safety is most likely to affect psychological, biological, and clinical outcomes. This is the conclusion ...

Years ago, the Canadian collector Bruce Bailey gave artist Curtis Talwst Santiago useful advice: “Be patient,” he said. At the time, Santiago was working on miniatures, making diminutive yet ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

This week, Columbia University scientists and their colleagues published a peer-reviewed study in Nature that unveils an AI foundation model capable of predicting gene activity across many ...

Total endothelial RNA from mouse lungs sorted by dynabeads was isolated with TRIzol reagent according to standard protocols and then sent to Beijing Novo Gene Company for RNA-sequencing analysis.

We demonstrated that ectopic expression of either LEF1 or β-catenin increased the promoter activity of the miR-17-92 cluster host gene (MIR17HG ... cell proliferation at least in part via direct ...