News

Nature6d
Crystal structure of a plant catechol oxidase containing a dicopper center
Catechol oxidases are ubiquitous plant enzymes containing a dinuclear copper center. In the wound-response mechanism of the plant they catalyze the oxidation of a broad range of ortho-diphenols to ...
C&EN2d
Synthesis, Characterization and Catalytic Activity of Iron, Cobalt and Nickel Complexes Bearing an N-Heterocyclic Carbene-Based PCP Pincer Ligand
Institute of Applied Synthetic Chemistry, TU Wien Getreidemarkt 9/163-AC, A-1060 Wien, Austria Centro de Química Estrutural, Institute of Molecular Sciences, Departamento de Engenharia Química, ...
C&EN2d
Are Automated Molecular Dynamics Simulations and Binding Free Energy Calculations Realistic Tools in Lead Optimization? An Evaluation of the Linear Interaction Energy (LIE) Method
Leiden/Amsterdam Center for Drug Research, Division of Molecular Toxicology, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands, Department of Chemistry, Biovitrum AB, ...