Drug transporter assays are many and varied because numerous transporter proteins require evaluation, and study designs are usually based around the availability of an appropriate test system to study ...

Drugs are eliminated in the kidney by glomerular filtration and/or tubular secretion. Uptake transporters in the basolateral membrane and export transporters in the luminal membrane of renal ...

Example 1: Cross-species comparison of drug handling of PAH excretion in the kidney transporter model Para-aminohippurate (PAH), a derivative of hippuric acid, is used to measure renal plasma flow.

utm_source=GNW This reports provides a data-driven overview of the current and future competitive landscape ... transporter inhibitors. - R&D activity in OCD is poor, with only two drug molecule ...