If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic ...

In fact, Watson and Crick were worried that they would be "scooped" by Pauling, who proposed a different model for the three-dimensional structure of DNA just months before they did. In the end ...

Abstract Faithful chromosome segregation requires the removal of all DNA bridges physically linking chromatids before the completion of cell division ...

However, incomplete DNA replication or chromosome ... The study was conducted using the model organism Caenorhabditis elegans, whose LEM-3 protein is evolutionarily conserved as ANKLE1 in humans.

If DNA bridges remain between chromosomes after cell division, chromosomes become improperly segregated, resulting in genetic ...

ATX-559, a first-in-class oral DHX9 inhibitor, is being evaluated in a Phase 1/2 study with a focuson advanced or metastatic ...

Computer simulations help materials scientists and biochemists study the motion of macromolecules, advancing the development of new drugs and ...

Researchers have identified a never-before-seen mechanism that enables HIV-1 to evade the body's natural defenses and use it ...

A chromosome glitch in beetleweed reveals how genome doubling can drive rapid plant evolution and create new species in real ...

About 3.7 billion years ago ... a naturally occurring catalyst and began the fateful process of self-assembled replication. One of the most fascinating questions in biology is how these simple ...

Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) ("Acurx" or the "Company"), a late-stage biopharmaceutical company developing a new class of antibiotics for difficult-to-treat bacterial infections, ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).